Rekombinanter MLH1 Antikörper (AA 450-500)
Kurzübersicht für Rekombinanter MLH1 Antikörper (AA 450-500) (ABIN7455102)
Target
Alle MLH1 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 450-500
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Verwendungszweck
- Rabbit anti-MLH1 Recombinant Monoclonal Antibody [BLR112H]
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Immunogen
- between AA 450 and 500
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 6 μL/1 mg lysate
ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 01:01,00
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- MLH1 (MutL Homolog 1 (MLH1))
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Andere Bezeichnung
- MLH1
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Hintergrund
- Background: MLH1 is an integral component of the DNA mismatch repair (MMR) system that functions to recognize aberrant structures and signals for the repair of single base mismatches or loops in replicated DNA. MLH1 can heterodimerize with DNA mismatch repair protein MLH3 and with mismatch repair endonuclease PMS2. [taken from NCBI Entrez Gene (Gene ID: 4292)].
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Gen-ID
- 4292
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NCBI Accession
- NP_000240
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UniProt
- P40692
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Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
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