Rekombinanter TP53BP1 Antikörper (AA 350-400)
Kurzübersicht für Rekombinanter TP53BP1 Antikörper (AA 350-400) (ABIN7455070)
Target
Alle TP53BP1 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
 - AA 350-400
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Verwendungszweck
 - Rabbit anti-53BP1 Recombinant Monoclonal Antibody [BL-250-1H11]
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Immunogen
 - between AA 350 and 400
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Isotyp
 - IgG
 
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Applikationshinweise
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IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 20 μL/mg lysate
WB: 17:40:00
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Konzentration
 - 100 μg/mL
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Buffer
 - Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
 - 4 °C
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Haltbarkeit
 - 12 months
 
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- TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
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Andere Bezeichnung
 - 53BP1
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Hintergrund
 - Background: 53BP1 (p53 Binding Protein 1) is an early participant in the cellular response to DNA double-strand breaks. 53BP1 functions in a redundant role in phosphorylation of the downstream checkpoint effector proteins Brca1 and Chk2 but was required for the formation of Brca1 foci in a hierarchical branched pathway for the recruitment of repair and signaling proteins to sites of DNA damage.
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Gen-ID
 - 7158
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NCBI Accession
 - NP_005648
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UniProt
 - Q12888
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Pathways
 - DNA Reparatur
 
Target
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