Mre11 Antikörper (AA 658-708)
Kurzübersicht für Mre11 Antikörper (AA 658-708) (ABIN7454999)
Target
Alle Mre11 (MRE11A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 658-708
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Verwendungszweck
- Rabbit anti-Mre11 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 658 and 708
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
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Andere Bezeichnung
- Mre11
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Hintergrund
- Background: Mre11 is a component of the MRN complex and plays a role in telomere maintenance and double-strand break (DSB) repair. Mre11 associates with rad50 in the MRN complex. Mre11 possesses 3'- 5' exonuclease activity that is involved in creating DNA termini in DSB suitable for priming DNA synthesis and ligation.
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Gen-ID
- 4361
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NCBI Accession
- NP_005582
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UniProt
- P49959
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Pathways
- DNA Reparatur
Target
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