beta Catenin Antikörper (AA 760-781)
Kurzübersicht für beta Catenin Antikörper (AA 760-781) (ABIN7454800)
Target
Alle beta Catenin (CATNB) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 760-781
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Verwendungszweck
- Rabbit anti-beta Catenin Antibody, Affinity Purified
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Homologie
- Rat,X. laevis,Bovine,Dog
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 760 and 781
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- beta Catenin (CATNB) (Catenin, beta (CATNB))
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Andere Bezeichnung
- beta Catenin
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Hintergrund
- Background: beta Catenin plays an integral role in the Wnt signaling pathway and is critical to morphogenic signaling and body axis specification. Beta Catenin exists in complexes with cadherins, transmembrane proteins that mediate cell adhesion. When Wnt-signaling proteins bind their receptors, beta Catenin is stabilized and accumulates in the cell. Translocation of stabilized beta Catenin allows its association with transcription factors and the activation of specific gene expression.
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Gen-ID
- 1499
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NCBI Accession
- NP_001895
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UniProt
- P35222
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Pathways
- Peptide Hormone Metabolism
Target
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