XPA Antikörper (AA 1-50)
Kurzübersicht für XPA Antikörper (AA 1-50) (ABIN7454782)
Target
Alle XPA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-50
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Verwendungszweck
- Rabbit anti-XPA Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 1 and 50
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:200 to 1:1000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))
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Andere Bezeichnung
- XPA
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Hintergrund
- Background: Mutations in XPA (xeroderma pigmentosum group A-complementing protein) are the cause of xeroderma pigmentosum A (XP-A), an autosomal recessive disease that is mainly characterized by a susceptibility to UV-induced skin cancer and in some cases neurological abnormalities. XPA is one of seven XP complementation groups that have been identified. The XP complementation groups represent genes critical to the nucleotide excision repair (NER) pathway. XPA is thought to function in the recognition of DNA damage and as a processivity factor for XPF and XPG.
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Gen-ID
- 7507
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NCBI Accession
- NP_000371
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UniProt
- P23025
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Pathways
- DNA Reparatur
Target
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