FEN1 Antikörper (AA 250-300)
Kurzübersicht für FEN1 Antikörper (AA 250-300) (ABIN7454602)
Target
Alle FEN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 250-300
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Verwendungszweck
- Rabbit anti-Fen1 Antibody, Affinity Purified
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Homologie
- Sheep,Bovine
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 250 and 300
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. 16-18 hour incubation is recommended.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))
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Andere Bezeichnung
- Fen1
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Hintergrund
- Background: Flap endonuclease 1 (Fen1) is a member of the XPG/RAD2 endonuclease family. Fen1 functions primarily as an endonuclease that removes 5'-overhangs during base-excision DNA repair and lagging strand DNA synthesis. For these processes Fen1 interacts with PCNA and the 9-1-1 DNA repair complex. Fen1 also possesses 5' to 3' exonuclease activity as well as RNase H activity.
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Gen-ID
- 2237
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NCBI Accession
- NP_004102
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UniProt
- P39748
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Pathways
- Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA
Target
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