Topoisomerase II alpha Antikörper (C-Term)
Kurzübersicht für Topoisomerase II alpha Antikörper (C-Term) (ABIN7454588)
Target
Alle Topoisomerase II alpha (TOP2A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- Rabbit anti-Topo II Alpha Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 1500 and C-term
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Isotyp
- IgG
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anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1352-1493) antibody
TOP2A Reaktivität: Human, Maus WB, IHC, IF Wirt: Maus Monoclonal TOP2A-1361 unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1100-1530) antibodyTOP2A Reaktivität: Human, Ratte WB, ELISA, FACS, ICC Wirt: Maus Monoclonal 6C12G12 unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) antibodyKD Validated TOP2A Reaktivität: Human WB, FACS, IF (p) Wirt: Kaninchen Monoclonal 24GB1915 unconjugated Recombinant Antibody
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) antibodyTOP2A Reaktivität: Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1435-1531) antibodyTOP2A Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1E2 unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 650-700) antibodyTOP2A Reaktivität: Human, Maus WB, IHC, ICC Wirt: Kaninchen Monoclonal BLR358N unconjugated Recombinant Antibody
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 650-700) antibodyTOP2A Reaktivität: Human, Maus WB, IHC, ICC Wirt: Kaninchen Monoclonal BLR358N unconjugated Recombinant Antibody
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1100-1530) antibodyTOP2A Reaktivität: Human WB, IHC, ELISA Wirt: Maus Monoclonal 6D4B2 unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1167-1196), (C-Term) antibodyTOP2A Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB24346 unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1352-1493) antibodyTOP2A Reaktivität: Human IHC Wirt: Kaninchen Monoclonal 802R unconjugated Recombinant Antibody
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Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:10,000 - 1:30,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
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Andere Bezeichnung
- Topo II Alpha
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Hintergrund
- Background: Topoisomerases regulate topological states of DNA and are divided into type I and type II enzymes. Type II topoisomerases make double stranded breaks in DNA and allow the passage of another duplex DNA across the break to achieve unknotting of entangled DNA. Topo II Alpha is one of two described isoforms that are likely products of a gene duplication event. TopoII Alpha is also described to be involved in chromosome condensation, chromatid separation, and the relief of supercoil stress.
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Gen-ID
- 7153
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NCBI Accession
- NP_001058
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UniProt
- P11388
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Pathways
- Zellzyklus, Mitotic G1-G1/S Phases
Target
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