MSH6 Antikörper (AA 350-400)
Kurzübersicht für MSH6 Antikörper (AA 350-400) (ABIN7454510)
Target
Alle MSH6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 350-400
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Verwendungszweck
- Goat anti-MSH6 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 350 and 400
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:250 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: Not recommended
WB: 1:1,000 - 1:5,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
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Andere Bezeichnung
- MSH6
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Hintergrund
- Background: MSH6 is a component of the DNA mismatch repair (MMR) system that functions to recognize base-base mismatches and framshift mispairs. MSH6 forms a heterodimer with MSH2 and is also part of the BRCA1-associated genome surveillance complex (BASC). Mutations in MSH6 have been linked to endometrial carcinoma.
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Gen-ID
- 2956
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NCBI Accession
- NP_000170
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UniProt
- P52701
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Pathways
- DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response
Target
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