RANGAP1 Antikörper (AA 400-450)
Kurzübersicht für RANGAP1 Antikörper (AA 400-450) (ABIN7454428)
Target
Alle RANGAP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 400-450
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Verwendungszweck
- Rabbit anti-RanGAP1 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 400 and 450
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-RanGAP1 antibody A302-026A.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))
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Andere Bezeichnung
- RanGAP1
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Hintergrund
- Background: The regulation of GTPase activity is achieved via activators called GEFs (guanine-nucleotide exchange factors) and inactivators called GAPs (GTPase-activating proteins). Ran-specific GTPase-activating protein 1 (RanGAP1) induces the GTPase activity of the RAN small GTPase. The Ran GTPase plays a role in spatial information and nucleocytoplasmic transport. RanGAP1 is the antagonist of the GEF RCC1 which keeps RAN in the active GTP-bound state.
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Gen-ID
- 5905
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NCBI Accession
- NP_002874
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UniProt
- P46060
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Pathways
- M Phase, Protein targeting to Nucleus
Target
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