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CHEK2 Antikörper (AA 475-525)

Dieses Anti-CHEK2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CHEK2 in IP und IHC (fp). Geeignet für Human.

Produktnummer ABIN7454369

Datenblatt (PDF)

Kurzübersicht für CHEK2 Antikörper (AA 475-525) (ABIN7454369)

Target

Alle CHEK2 Antikörper anzeigen

CHEK2 (Checkpoint Kinase 2 (CHEK2))

Reaktivität

Human

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

Dieser CHEK2 Antikörper ist unkonjugiert

Applikation

Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Discover our top product CHEK2 Primärantikörper

Bindungsspezifität
26

25

19

17

16

16

15

15

9

8

8

8

6

5

4

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 475-525

Verwendungszweck

Rabbit anti-Chk2 Antibody, Affinity Purified

Aufreinigung

Affinity Purified

Immunogen

between AA 475 and 525

Isotyp

IgG
anti-Checkpoint Kinase 2 (CHEK2) (pThr387) antibody
CHEK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 111-141), (N-Term) antibody
CHEK2 Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB19067 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 1-543) antibody
CHEK2 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 1-543) antibody
CHEK2 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 4B7 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pSer516) antibody
CHEK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pThr68) antibody
CHEK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pThr383) antibody
CHEK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 Reaktivität: Human, Hund WB, IHC, IP, IHC (p), FACS Wirt: Maus Monoclonal 2H5 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 Reaktivität: Human, Hund WB, IHC, IF, IP, IHC (p), FACS Wirt: Maus Monoclonal 5C4 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 Reaktivität: Human, Affe, Hund WB, IHC, IF, IHC (p), FACS Wirt: Maus Monoclonal 10G7 unconjugated

Applikationshinweise

IHC: 1:250 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 1 - 4 μg/mg lysate
WB: Not recommended. Use rabbit anti-Chk2 antibody A300-620A.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1000 μg/mL

Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C

Haltbarkeit

12 months
Target

CHEK2 (Checkpoint Kinase 2 (CHEK2))

Andere Bezeichnung

Chk2

Hintergrund

Background: Chk2 functions as a checkpoint protein kinase in response to DNA damage to maintain genomic stability. The yeast homologs are RAD53 and Cds1. The two major upstream controllers of Chk2 are ATM and ATR which are part of the phosphatidylinositol 3-kinase family. When activated, Chk2 targets p53, Brca1, Cdc25A and Cdc25C to cause cell cycle arrest. Chk2 is also known as serine/threonine-protein kinase CHK2, CHEK2, CDS1, LFS2, RAD53, HuCds1, and PP1425.

Gen-ID

11200

NCBI Accession

NP_009125

UniProt

O96017

Pathways

p53 Signalweg, Apoptose, Zellzyklus