Rekombinanter STAT5A Antikörper (AA 744-794)

Produktnummer ABIN7454017

Der Kaninchen Monoklonal Anti-STAT5A-Antikörper wurde für WB, IHC, IP, FACS und ICC validiert. Er ist geeignet, STAT5A in Proben von Human und Maus zu detektieren.

Kurzübersicht für Rekombinanter STAT5A Antikörper (AA 744-794) (ABIN7454017)

Target: STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser STAT5A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon: BLR124H

Produktdetails anti-STAT5A Antikörper

Bindungsspezifität: AA 744-794

Verwendungszweck: Rabbit anti-STAT5a Recombinant Monoclonal Antibody [BLR124H]

Immunogen: between AA 744 and 794 (C-term)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu STAT5A

Target: STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))

Andere Bezeichnung: STAT5a

Hintergrund: Background: Signal transducer and activator of transcription 5a (STAT5a) is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones [taken from NCBI Entrez Gene (Gene ID: 6776)].

Gen-ID: 6776

NCBI Accession: NP_001275647

UniProt: P42229

Pathways: JAK-STAT Signalweg, RTK Signalweg, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation