Rekombinanter MSH2 Antikörper (AA 625-675)
Kurzübersicht für Rekombinanter MSH2 Antikörper (AA 625-675) (ABIN7453978)
Target
Alle MSH2 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 625-675
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Verwendungszweck
- Rabbit anti-MSH2 Recombinant Monoclonal Antibody [BLR116H] - BSA-Free
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Aufreinigung
- Purified
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Immunogen
- between AA 625 and 675
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1000 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2 - 8 °C
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Haltbarkeit
- 12 months
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- MSH2 (Mismatch Repair Protein 2 (MSH2))
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Andere Bezeichnung
- MSH2
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Hintergrund
- MSH2 is an integral component of the DNA mismatch repair (MMR) system that functions to recognize aberrant structures and signals for the repair of single base mismatches or loops in replicated DNA. MSH2 has also been demonstrated to function as an anti-recombinase and may play a role in negatively regulating DNA repair. MSH2 can heterodimerize with MSH3 or MSH6. Mutations in MSH2 are linked to hereditary nonpolyposis colon cancer (HNPCC).
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Gen-ID
- 4436
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UniProt
- P43246
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Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
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