MAPKAP Kinase 5 Antikörper (AA 423-473)
Kurzübersicht für MAPKAP Kinase 5 Antikörper (AA 423-473) (ABIN7453731)
Target
Alle MAPKAP Kinase 5 (MAPKAPK5) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 423-473
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Verwendungszweck
- Rabbit anti-MK5 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 423 and 473
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- MAPKAP Kinase 5 (MAPKAPK5) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))
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Andere Bezeichnung
- MK5
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Hintergrund
- Background: MK5 (MAP kinase-activated protein kinase 5) is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. [taken from NCBI Entrez Gene (GeneID: 8550)].
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Gen-ID
- 8550
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NCBI Accession
- NP_620777
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UniProt
- Q8IW41
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Pathways
- MAPK Signalweg
Target
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