Interleukin enhancer-binding factor 3 (ILF3) (AA 1-50) Antikörper

Produktnummer ABIN7453538

Der Kaninchen Polyklonal Anti--Antikörper wurde für WB und IHC (fp) validiert. Er ist geeignet, in Proben von Human und Maus zu detektieren.

Kurzübersicht für Interleukin enhancer-binding factor 3 (ILF3) (AA 1-50) Antikörper (ABIN7453538)

Target: Interleukin enhancer-binding factor 3 (ILF3)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails

Bindungsspezifität: AA 1-50

Verwendungszweck: Rabbit anti-NF90/NF110 Antibody, Affinity Purified

Homologie: Rat

Aufreinigung: Affinity Purified

Immunogen: between AA 1 and 50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Antigendetails

Target: Interleukin enhancer-binding factor 3 (ILF3)

Andere Bezeichnung: NF90/NF110

Hintergrund: Background: NFAR (nuclear factor associated with dsRNA) exists as two major protein species of 90 kDa (NFAR-1 or NF90) and 110 kDa (NFAR-2 or NF110) in the cell. NF90 and NF110 arise from a single gene named interleukin enhancer binding factor (ILF3) gene which resides on chromosome 19p13 and are generated through alternative splicing events. NF90 is a dsRNA binding protein that stabilizes mRNAs and regulates transcription. NF90 is a subunit of the nuclear factor of activated T-cells (NFAT) transcription factor that is required for T-cell expression of interleukin 2. The NF110 isoform is restricted to the nucleus and its function may be unrelated to NF90.

Gen-ID: 3609

NCBI Accession: NP_036350

UniProt: Q12906

Pathways: M Phase