Interleukin enhancer-binding factor 3 (ILF3) Antikörper

Produktnummer ABIN7260443

Produktdetails

Target: Interleukin enhancer-binding factor 3 (ILF3)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human ILF3 (NP_036350.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Antigendetails

Target: Interleukin enhancer-binding factor 3 (ILF3)

Andere Bezeichnung: ILF3 (ILF3 Produkte)

Synonyme: CBTF antikoerper, DRBF antikoerper, DRBP76 antikoerper, MMP4 antikoerper, MPHOSPH4 antikoerper, MPP4 antikoerper, NF-AT-90 antikoerper, NF110 antikoerper, NF110b antikoerper, NF90 antikoerper, NF90a antikoerper, NF90b antikoerper, NFAR antikoerper, NFAR-1 antikoerper, NFAR2 antikoerper, TCP110 antikoerper, TCP80 antikoerper, MBII-26 antikoerper, ilf3 antikoerper, wu:fb37d07 antikoerper, wu:fb94b02 antikoerper, zgc:77030 antikoerper, 4F.1 antikoerper, cbtf122 antikoerper, ilf3-A antikoerper, ubp3 antikoerper, ubp4 antikoerper, xilf3 antikoerper, interleukin enhancer binding factor 3 antikoerper, interleukin enhancer binding factor 3b antikoerper, interleukin enhancer binding factor 3 S homeolog antikoerper, ILF3 antikoerper, Ilf3 antikoerper, ilf3b antikoerper, ilf3.S antikoerper

Hintergrund: This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht:

Observed_MW: 95 kDa/120 kDa

Calculated_MW: 74 kDa/75 kDa/76 kDa/82 kDa/95 kDa

Gen-ID: 3609

UniProt: Q12906

Pathways: M Phase