DCK Antikörper (AA 210-260)
Kurzübersicht für DCK Antikörper (AA 210-260) (ABIN7453430)
Target
Alle DCK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 210-260
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Verwendungszweck
- Rabbit anti-DCK Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 210 and 260
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- DCK (Deoxycytidine Kinase (DCK))
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Andere Bezeichnung
- DCK
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Hintergrund
- Background: Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivitiy [taken from NCBI Entrez Gene (Gene ID: 1633)].
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Gen-ID
- 1633
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NCBI Accession
- NP_000779
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UniProt
- P27707
Target
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