PARD3 Antikörper (AA 1306-1356)
Kurzübersicht für PARD3 Antikörper (AA 1306-1356) (ABIN7453156)
Target
Alle PARD3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 1306-1356
-
Verwendungszweck
- Rabbit anti-PARD3 Antibody, Affinity Purified
-
Homologie
- Rat
-
Aufreinigung
- Affinity Purified
-
Immunogen
- Between AA 1306 and 1356
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IP: Not recommended
WB: 1:2,000 - 1:10,000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))
-
Andere Bezeichnung
- PARD3
-
Hintergrund
- Background: Partitioning defective 3 homolog (Par3) is an adapter protein involved in asymmetrical cell division and cell polarization processes. It seems to play a central role in the formation of epithelial tight junctions and targets the phosphatase PTEN to cell junctions (By similarity). Par3 association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Par3 is required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons [taken from the Universal Protein Resource (UniProt) Q8TEW0].
-
Gen-ID
- 56288
-
NCBI Accession
- NP_062565
-
UniProt
- Q8TEW0
-
Pathways
- Cell-Cell Junction Organization
Target
-