PARD3 Antikörper (C-Term)

Produktnummer ABIN6259144

Produktdetails anti-PARD3 Antikörper

Target: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: PARD3 Antibody detects endogenous levels of total PARD3.

Homologie: Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PARD3, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PARD3

Target: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Andere Bezeichnung: PARD3 (PARD3 Produkte)

Synonyme: ASIP antikoerper, Baz antikoerper, PAR3 antikoerper, PAR3alpha antikoerper, PARD-3 antikoerper, PARD3A antikoerper, SE2-5L16 antikoerper, SE2-5LT1 antikoerper, SE2-5T2 antikoerper, Par3 antikoerper, AA960621 antikoerper, AI256638 antikoerper, D8Ertd580e antikoerper, PAR-3 antikoerper, Pard3a antikoerper, asip antikoerper, bazooka antikoerper, par-3 antikoerper, par3 antikoerper, pard3 antikoerper, par-3 family cell polarity regulator antikoerper, partitioning defective 3 homolog antikoerper, par-3 family cell polarity regulator alpha, b antikoerper, par-3 family cell polarity regulator S homeolog antikoerper, PARD3 antikoerper, Pard3 antikoerper, LOC100551156 antikoerper, LOC100473914 antikoerper, pard3 antikoerper, pard3ab antikoerper, pard3.S antikoerper

Hintergrund:

Description: Adapter protein involved in asymmetrical cell division and cell polarization processes (PubMed:27925688, PubMed:10954424). Seems to play a central role in the formation of epithelial tight junctions (PubMed:27925688). Targets the phosphatase PTEN to cell junctions (By similarity). Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly (By similarity). The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (PubMed:10934474). Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons (PubMed:19812038, PubMed:27925688).

Gene: PARD3

Molekulargewicht: 151 kDa

Gen-ID: 56288

UniProt: Q8TEW0

Pathways: Cell-Cell Junction Organization