PARD3 Antikörper (C-Term)

Produktnummer ABIN652622

Der Kaninchen Polyklonal anti-PARD3 Antikörper wird verwendet zum Nachweis von PARD3 in Proben von Human und Maus. Er wurde validiert für WB, FACS und IHC (p).

Kurzübersicht für PARD3 Antikörper (C-Term) (ABIN652622)

Target: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB21955

Produktdetails anti-PARD3 Antikörper

Bindungsspezifität: AA 1329-1356, C-Term

Homologie: Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PARD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1329-1356 amino acids from the C-terminal region of human PARD3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PARD3

Target: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Andere Bezeichnung: PARD3

Hintergrund: PARD proteins, which were first identified in C. elegans, are essential for asymmetric cell division and polarized growth, whereas CDC42 (MIM 116952) mediates the establishment of cell polarity. The CDC42 GTPase, which is controlled by nucleotide exchange factors (GEFs, see MIM 606057) and GTPase-activating proteins (GAPs, see MIM 604980), interacts with a large set of effector proteins that typically contain a CDC42/RAC (MIM 602048)-interactive binding (CRIB) domain.

Molekulargewicht: 151423

Gen-ID: 56288

NCBI Accession: NP_001171714, NP_001171715, NP_001171716, NP_001171717, NP_001171718, NP_001171719, NP_001171720, NP_001171721, NP_001171722, NP_001171723, NP_062565

UniProt: Q8TEW0

Pathways: Cell-Cell Junction Organization