P4HB Antikörper (AA 50-100)
Kurzübersicht für P4HB Antikörper (AA 50-100) (ABIN7453155)
Target
Alle P4HB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 50-100
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Verwendungszweck
- Rabbit anti-P4HB/PDI Antibody, Affinity Purified
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Homologie
- Rat,Bovine,Orangutan
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 50 and 100
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Isotyp
- IgG
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Applikationshinweise
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IP: Not recommended
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
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Andere Bezeichnung
- P4HB/PDI
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Hintergrund
- Background: P4HB is a multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, P4HB seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. Inside the cell, it seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, P4HB functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, it facilitates aggregation (anti-chaperone activity) [taken from the Universal Protein Resource (UniProt) P07237].
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Gen-ID
- 5034
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NCBI Accession
- NP_000909
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UniProt
- P07237
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Pathways
- Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism
Target
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