Dynactin 1 Antikörper (AA 1100-1150)
Kurzübersicht für Dynactin 1 Antikörper (AA 1100-1150) (ABIN7452530)
Target
Alle Dynactin 1 (DCTN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1100-1150
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Verwendungszweck
- Rabbit anti-p150glued Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 1100 and 1150
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: Not recommended
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Dynactin 1 (DCTN1)
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Andere Bezeichnung
- p150glued
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Hintergrund
- Background: p150glued is the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. The p150glued subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus [taken from NCBI Entrez Gene (Gene ID: 1639)].
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Gen-ID
- 1639
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NCBI Accession
- NP_004073
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UniProt
- Q14203
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Pathways
- M Phase, ER-Nucleus Signaling
Target
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