PAK1 Antikörper (AA 40-90)
Kurzübersicht für PAK1 Antikörper (AA 40-90) (ABIN7452386)
Target
Alle PAK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 40-90
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Verwendungszweck
- Rabbit anti-PAK1 Antibody, Affinity Purified
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Homologie
- Mouse,Rat,Bovine
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 40 and 90
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-PAK1 antibody ABIN7451931.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- PAK1 (P21-Activated Kinase 1 (PAK1))
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Andere Bezeichnung
- PAK1
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Hintergrund
- Background: PAK1 (p21-activated kinase 1) is part of the family of PAK serine/threonine p21-activating protein kinases involved in cell survival, migration, and invasion. PAK1 mediates signals from extracellular stimuli to the cytoplasm and nucleus via its association with the small GTP-binding proteins, Cdc42 and Rac. GTPase binding to PAK1 activates PAK1 kinase activity and leads to reorganization of the actin cytoskeleton and the phosphorylation of proteins involved in survival, energy metabolism, gene expression, cell motility, cell morphology, and the cell cycle.
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Gen-ID
- 5058
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NCBI Accession
- NP_002567
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UniProt
- Q13153
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Pathways
- MAPK Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis
Target
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