Acetyl-CoA Carboxylase alpha Antikörper (AA 1925-1975)

Produktnummer ABIN7452256

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Acetyl-CoA Carboxylase alpha in IP. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Acetyl-CoA Carboxylase alpha Antikörper (AA 1925-1975) (ABIN7452256)

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Acetyl-CoA Carboxylase alpha Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Produktdetails anti-Acetyl-CoA Carboxylase alpha Antikörper

Bindungsspezifität: AA 1925-1975

Verwendungszweck: Rabbit anti-ACC1/ACC-alpha Antibody, Affinity Purified

Homologie: Mouse,Rat

Aufreinigung: Affinity Purified

Immunogen: between AA 1925 and 1975

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-ACC1/ACC-alpha antibody ABIN7452869.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu Acetyl-CoA Carboxylase alpha

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Andere Bezeichnung: ACC1/ACC-alpha

Hintergrund: Background: ACC1/ACC-alpha catalyzes the carboxylation of acetyl-CoA to malonyl-CoA in the enzymatic pathway of long-chain fatty-acid synthesis. ACC1/ACC-alpha has been identified as a partner of BRCA1. Through this interaction, ACC1/ACC-alpha may contribute to the tumor suppressor activity of BRCA1 as demonstrated by the finding that disruption of this interaction increases lipid synthesis in mammary epithelial cells. In this context, lipogenesis has been closely linked to tumorigenesis and ACC1/ACC-alpha has been found to be highly expressed in human breast carcinomas.

Gen-ID: 31

NCBI Accession: NP_942131

UniProt: Q13085

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effekt