CARD11 Antikörper (AA 475-525)
Kurzübersicht für CARD11 Antikörper (AA 475-525) (ABIN7451677)
Target
Alle CARD11 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 475-525
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Verwendungszweck
- Rabbit anti-CARMA1 Antibody, Affinity Purified
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Homologie
- Mouse
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 475 and 525
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
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Andere Bezeichnung
- CARMA1
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Hintergrund
- Background: CARD-containing MAGUK protein 1 (CARMA1) belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). When expressed in cells, CARMA1 activates NF-kappaB and induces the phosphorylation of BCL10 [taken from NCBI Entrez Gene (GeneID: 84433)].
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Gen-ID
- 84433
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NCBI Accession
- NP_115791
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UniProt
- Q9BXL7
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Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, BCR Signaling
Target
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