CARD11 Antikörper (AA 275-325)
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- Target Alle CARD11 Antikörper anzeigen
- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
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Bindungsspezifität
- AA 275-325
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CARD11 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP)
- Verwendungszweck
- Rabbit anti-CARMA1 Antibody, Affinity Purified
- Homologie
- Mouse
- Aufreinigung
- Affinity Purified
- Immunogen
- between AA 275 and 325
- Isotyp
- IgG
- Top Product
- Discover our top product CARD11 Primärantikörper
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- Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
- Andere Bezeichnung
- CARMA1 (CARD11 Produkte)
- Hintergrund
- Background: CARD-containing MAGUK protein 1 (CARMA1) belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). When expressed in cells, CARMA1 activates NF-kappaB and induces the phosphorylation of BCL10 [taken from NCBI Entrez Gene (GeneID: 84433)].
- Gen-ID
- 84433
- NCBI Accession
- NP_115791
- UniProt
- Q9BXL7
- Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, BCR Signaling
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