Fibrillarin Antikörper (AA 271-321)
Kurzübersicht für Fibrillarin Antikörper (AA 271-321) (ABIN7449735)
Target
Alle Fibrillarin (FBL) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 271-321
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Verwendungszweck
- Rabbit anti-Fibrillarin Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 271 and 321
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:1,000 - 1:5,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Fibrillarin (FBL)
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Andere Bezeichnung
- Fibrillarin
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Hintergrund
- Background: Fibrillarin is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. Fibrillarin contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin [taken from NCBI Entrez Gene (Gene ID: 2091)].
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Gen-ID
- 2091
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NCBI Accession
- NP_001427
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UniProt
- P22087
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Pathways
- Ribonucleoside Biosynthetic Process
Target
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