Retinoblastoma 1 Antikörper (AA 550-600)
Kurzübersicht für Retinoblastoma 1 Antikörper (AA 550-600) (ABIN7449625)
Target
Alle Retinoblastoma 1 (RB1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 550-600
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Verwendungszweck
- Rabbit anti-Rb1 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 550 and 600
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Isotyp
- IgG
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anti-Retinoblastoma 1 (RB1) (pSer780) antibody
RB1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (AA 586-615) antibodyRB1 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB7977 unconjugated
anti-Retinoblastoma 1 (RB1) (AA 858-886), (C-Term) antibodyRB1 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB20715 unconjugated
anti-Retinoblastoma 1 (RB1) (pSer612) antibodyRB1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB7659 unconjugated
anti-Retinoblastoma 1 (RB1) (pSer780) antibodyRB1 Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated
anti-Retinoblastoma 1 (RB1) (C-Term) antibodyRB1 Reaktivität: Human WB, IF, IP, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (C-Term) antibodyRB1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (pSer807) antibodyRB1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (pSer795) antibodyRB1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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IP: 10 - 15 μg/mg lysate
WB: Not recommended.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Retinoblastoma 1 (RB1)
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Andere Bezeichnung
- Rb1
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Hintergrund
- Background: Retinoblastoma 1 (Rb1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. Rb1 has also been found to stabilize constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma [taken from NCBI Entrez Gene (GeneID: 5925)].
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Gen-ID
- 5925
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NCBI Accession
- NP_000312
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UniProt
- P06400
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Pathways
- Zellzyklus, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagie
Target
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