RAD17 Antikörper (pSer645)
Kurzübersicht für RAD17 Antikörper (pSer645) (ABIN7449387)
Target
Alle RAD17 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer645
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Verwendungszweck
- Rabbit anti-Phospho Rad17 (S645) Antibody, Affinity Purified
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Homologie
- Orangutan
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Aufreinigung
- Affinity Purified
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Immunogen
- surrounding serine 645
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
WB: 1:1,000 - 1:5,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- RAD17
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Andere Bezeichnung
- Rad17
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Hintergrund
- Background: Rad17 is a cell cycle checkpoint protein that associates with the RFC complex to recruit the 9-1-1 complex (Rad9, Hus1, Rad1) to sites of DNA damage. At DNA lesions, Rad17 and RFC aid in the activation of Chk2 by ATM and ATRIP to trigger the checkpoint signaling cascade for G2 arrest.
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Gen-ID
- 5884
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NCBI Accession
- NP_002864
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UniProt
- O75943
Target
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