Rad6 (AA 100-150) Antikörper

Produktnummer ABIN7449272

Produktdetails

Target: Rad6

Bindungsspezifität: AA 100-150

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit anti-Rad6 Antibody, Affinity Purified

Homologie: Mouse,Rat,Bovine,Rabbit

Aufreinigung: Affinity Purified

Immunogen: between AA 100 and 150

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1:5,000 - 1:25,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Antigendetails

Target: Rad6

Hintergrund: Background: Rad 6, also known as Ubiquitin conjugating enzyme E2A, is an E2 enzyme of the three step ubiquitination pathway. Targeting of proteins by ubiquitination occurs in three main steps that involve the activation of ubiquitin by E1 enzymes, the carrying of ubiquitin to the target protein by E2 enzymes, and the ligation of ubiquitin to the target protein by E3 enzymes. Ubiquitination provides an important post-translational means to regulate protein abundance and activity. Rad6 has been demonstrated to be important to DNA damage repair. Mutations in Rad6 cause an X-linked mental retardation syndrome.

Gen-ID: 7319

NCBI Accession: NP_003327

UniProt: P49459