Rad6 (N-Term) Antikörper

Produktnummer ABIN7448752

Produktdetails

Target: Rad6

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC)

Verwendungszweck: Rabbit anti-Rad6 IHC Antibody, Affinity Purified

Homologie: Rat,D. melanogaster,Zebrafish,X. laevis,X. tropicalis,Chicken,Bovine,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Atlantic salmon,Tasmanian devil,Rainbow smelt,Rainbow trout,Nile tilapia,Ferret,Yeast_237561,Killifish,African elephant,Medaka fish,Thirteen-lined ground squirrel,Yeast_284593,Zebra finch,Little brown bat,Teleostei,Small-eared galago,Japanese pufferfish,Naked mole rat,Green anole,Northern white-cheeked gibbon,Sablefish,Red sea bream,Northern pike,West Indian ocean coelacanth,Baker's yeast_559292,Spotted green pufferfish,Three-spined stickleback,Yeast_284811,Yeast_284590

Aufreinigung: Affinity Purified

Immunogen: N-terminus

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Antigendetails

Target: Rad6

Hintergrund: Background: Rad 6, also known as Ubiquitin conjugating enzyme E2A, is an E2 enzyme of the three step ubiquitination pathway. Targeting of proteins by ubiquitination occurs in three main steps that involve the activation of ubiquitin by E1 enzymes, the carrying of ubiquitin to the target protein by E2 enzymes, and the ligation of ubiquitin to the target protein by E3 enzymes. Ubiquitination provides an important post-translational means to regulate protein abundance and activity. Rad6 has been demonstrated to be important to DNA damage repair. Mutations in Rad6 cause an X-linked mental retardation syndrome.

Gen-ID: 7319

NCBI Accession: NP_003327

UniProt: P49459