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BRCA1 Antikörper (AA 700-750)

Name: BRCA1 Antikörper (AA 700-750)
Brand: antibodies-online
SKU: ABIN7448934
Price: 618.83 EUR
Availability: InStock

Dieses Anti-BRCA1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BRCA1 in IHC und IF (p). Geeignet für Human.

Produktnummer ABIN7448934

Kurzübersicht für BRCA1 Antikörper (AA 700-750) (ABIN7448934)

Target

Alle BRCA1 Antikörper anzeigen

BRCA1 (Breast Cancer 1 (BRCA1))

Reaktivität

Human

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

Dieser BRCA1 Antikörper ist unkonjugiert

Applikation

Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Discover our top product BRCA1 Primärantikörper

Bindungsspezifität
33

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AA 700-750

Verwendungszweck

Rabbit anti-BRCA1 IHC Antibody, Affinity Purified

Homologie

Orangutan,Gorilla,Chimpanzee,Northern white-cheeked gibbon,Brown-headed spider monkey,Bornean orangutan,Long-haired spider monkey,Agile gibbon

Aufreinigung

Affinity Purified

Immunogen

Between AA 700 and 750

Isotyp

IgG
anti-Breast Cancer 1 (BRCA1) (AA 19-83) antibody
BRCA1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Breast Cancer 1 (BRCA1) (pSer1423) antibody
BRCA1 Reaktivität: Human, Ratte, Maus WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Breast Cancer 1 (BRCA1) (AA 229-335) antibody
BRCA1 Reaktivität: Human IHC, ELISA Wirt: Maus Monoclonal 6C6D2 unconjugated

anti-Breast Cancer 1 (BRCA1) (AA 1661-1863) antibody
BRCA1 Reaktivität: Human, Ratte, Maus WB, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-Breast Cancer 1 (BRCA1) (Ser184), (Ser186) antibody
BRCA1 Reaktivität: Human, Ratte WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Breast Cancer 1 (BRCA1) (AA 445-620) antibody
BRCA1 Reaktivität: Human IHC, ISt, StM Wirt: Maus Monoclonal BRCA1-1398 unconjugated

anti-Breast Cancer 1 (BRCA1) (AA 1314-1600), (AA 1314-1864) antibody
BRCA1 Reaktivität: Human WB, IF, IP, FACS, ICC Wirt: Maus Monoclonal RAY unconjugated

anti-Breast Cancer 1 (BRCA1) (AA 1524-1781) antibody
BRCA1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Breast Cancer 1 (BRCA1) (AA 64-160) antibody
BRCA1 Reaktivität: Ratte, Maus ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Breast Cancer 1 (BRCA1) (pSer1524) antibody
BRCA1 Reaktivität: Human ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

IHC-IF: 1:50 - 1:500
IHC: 1:100 - 1:500

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

250 μg/mL

Buffer

Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C

Haltbarkeit

12 months
Target

BRCA1 (Breast Cancer 1 (BRCA1))

Andere Bezeichnung

BRCA1

Hintergrund

Background: BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination.

Gen-ID

672

NCBI Accession

NP_009225

UniProt

P38398

Pathways

Zellzyklus, DNA Reparatur, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus