RANGAP1 Antikörper (AA 400-450)

Produktnummer ABIN7448754

Produktdetails anti-RANGAP1 Antikörper

Target: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Bindungsspezifität: AA 400-450

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RANGAP1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Verwendungszweck: Rabbit anti-RanGAP1 IHC Antibody, Affinity Purified

Homologie: Orangutan,Chimpanzee,Northern white-cheeked gibbon

Aufreinigung: Affinity Purified

Immunogen: Between AA 400 and 450

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu RANGAP1

Target: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Andere Bezeichnung: RanGAP1 (RANGAP1 Produkte)

Hintergrund: Background: The regulation of GTPase activity is achieved via activators called GEFs (guanine-nucleotide exchange factors) and inactivators called GAPs (GTPase-activating proteins). Ran-specific GTPase-activating protein 1 (RanGAP1) induces the GTPase activity of the RAN small GTPase. The Ran GTPase plays a role in spatial information and nucleocytoplasmic transport. RanGAP1 is the antagonist of the GEF RCC1 which keeps RAN in the active GTP-bound state.

Gen-ID: 5905

NCBI Accession: NP_002874

UniProt: P46060

Pathways: M Phase, Protein targeting to Nucleus