Cyclin C Antikörper (AA 244-294)

Produktnummer ABIN7448506

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cyclin C in IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Cyclin C Antikörper (AA 244-294) (ABIN7448506)

Target: Cyclin C (CCNC)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin C Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-Cyclin C Antikörper

Bindungsspezifität: AA 244-294

Verwendungszweck: Rabbit anti-Cyclin C IHC Antibody, Affinity Purified

Homologie: Mouse,Rat,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Tasmanian devil,White-tufted-ear marmoset,Small-eared galago,Little brown bat,Naked mole rat,Thirteen-lined ground squirrel,Chinese hamster,Crab-eating macaque,Duckbill platypus,Gray short-tailed opossum,Zebra finch,Northern white-cheeked gibbon

Aufreinigung: Affinity Purified

Immunogen: Between AA 244 and 294

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu Cyclin C

Target: Cyclin C (CCNC)

Andere Bezeichnung: Cyclin C

Hintergrund: Background: Cyclin C is a member of the cyclin family of regulatory proteins that associate with and activate cyclin-dependent kinases (CDKs) to regulate cell cycle progression. Cyclins exhibit periodicity in their expression and activity which is regulated transcriptionally and post-transcriptionally via phosphorylation and ubiquitination. Cyclin C associates with cyclin-dependent kinase 8 (CDK8). It is also a component of the Mediator complex, a coactivator complex that provides a scaffold to link gene-specific transcription factors to RNA polymerase II and the general transcription machinery.

Gen-ID: 892

NCBI Accession: NP_005181

UniProt: P24863

Pathways: Zellzyklus, Regulation of Lipid Metabolism by PPARalpha