MYBL2 Antikörper (AA 450-500)
Kurzübersicht für MYBL2 Antikörper (AA 450-500) (ABIN7448426)
Target
Alle MYBL2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 450-500
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Verwendungszweck
- Rabbit anti-B-Myb IHC Antibody, Affinity Purified
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Homologie
- Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Crab-eating macaque,Ferret,Small-eared galago,Northern white-cheeked gibbon,White-tufted-ear marmoset,Thirteen-lined ground squirrel
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 450 and 500
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Isotyp
- IgG
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Applikationshinweise
- 1:100 - 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 250 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))
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Andere Bezeichnung
- B-Myb
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Hintergrund
- Background: B-myb is transcription factor involved in multiple cellular processes such as cell survival, proliferation, and differentiation. B-myb was identified in a low-stringency screen of a T-cell cDNA library probed with a C-myb probe. C-myb is a cellular proto-oncogene highly conserved in vertebrates and invertebrates. The chicken c-myb proto-oncogene was the first ortholog discovered. Investigation of the origins of the avian myeloblastosis virus (AMV) led to the discovery that the AMV genome contained transduced sequences from normal chicken cellular DNA that resulted in a viral oncogenic version (v-myb) of the c-myb gene. B-myb is cell cycle regulated and expressed in all proliferating cells. Recent studies show that it is the only myb family member detected in embryonic stem cells and is essential to cell cycle progression and genomic stability.
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Gen-ID
- 4605
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NCBI Accession
- NP_002457
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UniProt
- P10244
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Pathways
- Zellzyklus, Mitotic G1-G1/S Phases, Chromatin Binding
Target
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