MYBL2 Antikörper (AA 450-500)

Produktnummer ABIN7448426

Der Kaninchen-Polyklonal Anti-MYBL2-Antikörper wurde für IHC validiert. Er ist geeignet zum Nachweis von MYBL2 in Proben aus Human. }

Kurzübersicht für MYBL2 Antikörper (AA 450-500) (ABIN7448426)

Target: MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYBL2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-MYBL2 Antikörper

Bindungsspezifität: AA 450-500

Verwendungszweck: Rabbit anti-B-Myb IHC Antibody, Affinity Purified

Homologie: Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Crab-eating macaque,Ferret,Small-eared galago,Northern white-cheeked gibbon,White-tufted-ear marmoset,Thirteen-lined ground squirrel

Aufreinigung: Affinity Purified

Immunogen: Between AA 450 and 500

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu MYBL2

Target: MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))

Andere Bezeichnung: B-Myb

Hintergrund: Background: B-myb is transcription factor involved in multiple cellular processes such as cell survival, proliferation, and differentiation. B-myb was identified in a low-stringency screen of a T-cell cDNA library probed with a C-myb probe. C-myb is a cellular proto-oncogene highly conserved in vertebrates and invertebrates. The chicken c-myb proto-oncogene was the first ortholog discovered. Investigation of the origins of the avian myeloblastosis virus (AMV) led to the discovery that the AMV genome contained transduced sequences from normal chicken cellular DNA that resulted in a viral oncogenic version (v-myb) of the c-myb gene. B-myb is cell cycle regulated and expressed in all proliferating cells. Recent studies show that it is the only myb family member detected in embryonic stem cells and is essential to cell cycle progression and genomic stability.

Gen-ID: 4605

NCBI Accession: NP_002457

UniProt: P10244

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, Chromatin Binding