Interleukin enhancer-binding factor 3 (ILF3) Antikörper

Produktnummer ABIN7384360

Dieses Anti--Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von in WB, IF und IHC (p). Geeignet für Human und Ratte.

Kurzübersicht für Interleukin enhancer-binding factor 3 (ILF3) Antikörper (ABIN7384360)

Target: Interleukin enhancer-binding factor 3 (ILF3)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: R04-3C1

Produktdetails

Aufreinigung: Affinity Purified

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:2000-1:5000 IHC 1:50-1:100 IF 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Antigendetails

Target: Interleukin enhancer-binding factor 3 (ILF3)

Andere Bezeichnung: ILF3

Hintergrund: CBTF,Double stranded RNA binding protein 76,Double-stranded RNA-binding protein 76,DRBF,DRBP76,ILF3,ILF3,Interleukin enhancer binding factor 3,Interleukin enhancer-binding factor 3,M phase phosphoprotein 4,M-phase phosphoprotein 4,MPHOSPH4,MPP4,NF AT 90,NF-AT-90,NF110,NF90,NFAR,Nuclear factor associated with dsRNA,Nuclear factor of activated T cells 90 kDa,Nuclear factor of activated T-cells 90 kDa,TCP80,Translational control protein 80,This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht:

Observed_MW: 95kDa

Calculated_MW: 95kDa

Gen-ID: 3609

UniProt: Q12906

Pathways: M Phase