Lactate Dehydrogenase A Antikörper

Produktnummer ABIN7384336

Dieses Anti-Lactate Dehydrogenase A-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von Lactate Dehydrogenase A in WB. Geeignet für Human und Ratte.

Kurzübersicht für Lactate Dehydrogenase A Antikörper (ABIN7384336)

Target: Lactate Dehydrogenase A (LDHA)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Lactate Dehydrogenase A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: R09-9A7

Produktdetails anti-Lactate Dehydrogenase A Antikörper

Aufreinigung: Affinity Purified

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Lactate Dehydrogenase A

Target: Lactate Dehydrogenase A (LDHA)

Andere Bezeichnung: Lactate Dehydrogenase A

Hintergrund: Cell proliferation-inducing gene 19 protein,GSD11,L lactate dehydrogenase A chain,l7R2,LDH M,LDH muscle subunit,LDH1,PIG19 Proliferation-inducing gene 19,LDHA,also named as LDH-M and NY-REN-59,is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues,though predominantly in muscle tissue and tumours,and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development,invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.

Molekulargewicht:

Observed_MW: 37kDa

Calculated_MW: 37kDa

Gen-ID: 3939

UniProt: P00338

Pathways: Warburg Effekt