Lactate Dehydrogenase A Antikörper (Middle Region)

Produktnummer ABIN2785876

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Lactate Dehydrogenase A in WB, IHC und IP. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Kaninchen, Rind (Kuh), Pferd, Hund, Meerschweinchen, Ziege und Zebrafisch (Danio rerio).Es wurde in 1 Publikation zitiert.

Kurzübersicht für Lactate Dehydrogenase A Antikörper (Middle Region) (ABIN2785876)

Target: Lactate Dehydrogenase A (LDHA)

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Pferd, Hund, Meerschweinchen, Ziege, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lactate Dehydrogenase A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-Lactate Dehydrogenase A Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: LDHA Antibody - middle region

Sequenz: PLSCHGWVLG EHGDSSVPVW SGMNVAGVSL KTLHPDLGTD KDKEQWKEVH

Homologie: Cow: 79%, Dog: 86%, Goat: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against LDHA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LDHA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104126

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Lactate Dehydrogenase A Antikörper (ABIN2785876)

Listerman, Bledau, Grishina, Neugebauer: "Extragenic accumulation of RNA polymerase II enhances transcription by RNA polymerase III." in: PLoS genetics, Vol. 3, Issue 11, pp. e212, (2008) (PubMed).

Details zu Lactate Dehydrogenase A

Target: Lactate Dehydrogenase A (LDHA)

Andere Bezeichnung: LDHA

Hintergrund:

Background Information: The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene.

Gene Name: lactate dehydrogenase A

Alternative Symbols: LDHM, GSD11, PIG19, HEL-S-133P

Protein Name: L-lactate dehydrogenase A chain

Molekulargewicht: 37kDa

Gen-ID: 3939

NCBI Accession: NP_005557

UniProt: P00338

Pathways: Warburg Effekt