Integrin Alpha2b Antikörper

Produktnummer ABIN7271758

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Integrin Alpha2b in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Integrin Alpha2b Antikörper (ABIN7271758)

Target: Integrin Alpha2b (CD41)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Integrin Alpha2b Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Güteklasse: GMP Grade

Klon: 962C1

Produktdetails anti-Integrin Alpha2b Antikörper

Verwendungszweck: CD41a Unconjugated Antibody

Produktmerkmale: The clone 962C1, a mouse monoclonal antibody, reacts with the human CD41 Molecule, the integrin alpha-IIb also known as platelet GPIIb. CD41 is composed of two subunits GPIIbα (120 kDa) and GPIIbβ (23  kDa) that interact with CD61 to form a functional protein receptor in the presence of calcium. This protein receptor involves in the blood coagulation system, by mediating platelet adhesion and aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins like von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocytes and platelets. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder

Aufreinigung: Purified

Reinheit: >95 %

Immunogen: Recombinant full-length human Integrin alpha IIb protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Andere Bezeichnung: CD41a

Gen-ID: 3674

UniProt: P08514

Pathways: Integrin Complex