14-3-3 sigma/SFN Antikörper
Kurzübersicht für 14-3-3 sigma/SFN Antikörper (ABIN7270602)
Target
Alle 14-3-3 sigma/SFN (SFN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- 14-3-3 sigma Rabbit mAb
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Monoclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthesized peptide derived from human 14-3-3 sigma
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
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Andere Bezeichnung
- SFN
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Hintergrund
- Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.,YWHAS,Cell Biology & Developmental Biology,Cell Cycle,Cell Type Marker,Cell Type Marker_Neuron marker,Cell Type Marker_Synapse marker,Epigenetics & Nuclear Signaling,G2/M DNA Damage Checkpoint,MAPK-Erk Signaling Pathway,Neuroscience,Signal Transduction,Stem Cells,SFN
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Molekulargewicht
- 28kDa
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Gen-ID
- 2810
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UniProt
- P31947
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Pathways
- p53 Signalweg, Myometrial Relaxation and Contraction
Target
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