NXF1 Antikörper (AA 57-356)

Produktnummer ABIN7269024

Dieses Anti-NXF1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NXF1 in WB. Geeignet für Human.

Kurzübersicht für NXF1 Antikörper (AA 57-356) (ABIN7269024)

Target: NXF1 (Nuclear RNA Export Factor 1 (NXF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NXF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NXF1 Antikörper

Bindungsspezifität: AA 57-356

Verwendungszweck: NXF1 Rabbit pAb

Sequenz: GDVAMSDAQD GPRVRYNPYT TRPNRRGDTW HDRDRIHVTV RRDRAPPERG GAGTSQDGTS KNWFKITIPY GRKYDKAWLL SMIQSKCSVP FTPIEFHYEN TRAQFFVEDA STASALKAVN YKILDRENRR ISIIINSSAP PHTILNELKP EQVEQLKLIM SKRYDGSQQA LDLKGLRSDP DLVAQNIDVV LNRRSCMAAT LRIIEENIPE LLSLNLSNNR LYRLDDMSSI VQKAPNLKIL NLSGNELKSE RELDKIKGLK LEELWLDGNS LCDTFRDQST YIRSVVACVS PPGDLHPLGG

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 57-356 of human NXF1 (NP_001074960.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NXF1

Target: NXF1 (Nuclear RNA Export Factor 1 (NXF1))

Andere Bezeichnung: NXF1

Hintergrund: This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants.,NXF1,MEX67,TAP,Epigenetics & Nuclear Signaling,RNA Binding,NXF1

Molekulargewicht: 40kDa/70kDa

Gen-ID: 10482

UniProt: Q9UBU9