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NXF1 Antikörper (C-Term)

NXF1 Reaktivität: Human WB, IP, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855276
  • Target Alle NXF1 Antikörper anzeigen
    NXF1 (Nuclear RNA Export Factor 1 (NXF1))
    Bindungsspezifität
    • 12
    • 12
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 55
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    Human
    Wirt
    • 55
    • 1
    Kaninchen
    Klonalität
    • 46
    • 10
    Polyklonal
    Konjugat
    • 29
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser NXF1 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 22
    • 19
    • 8
    • 7
    • 5
    • 4
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Sequenz
    CSSGALDYDI PTTASENLYF Q
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Rabbit Polyclonal antibody to TAP (nuclear RNA export factor 1)
    TAP antibody [C2C3], C-term
    Aufreinigung
    Affinity purified by Protein A.
    Immunogen
    Recombinant protein encompassing a sequence within the C-terminus region of human TAP. The exact sequence is proprietary.
    Isotyp
    IgG
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  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: Mouse brain , A431

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    10.00 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    NXF1 (Nuclear RNA Export Factor 1 (NXF1))
    Andere Bezeichnung
    nuclear RNA export factor 1 (NXF1 Produkte)
    Synonyme
    im:7156527 antikoerper, wu:fc12d06 antikoerper, MGC82224 antikoerper, NXF1 antikoerper, tap antikoerper, mex67 antikoerper, MEX67 antikoerper, TAP antikoerper, Mex67 antikoerper, Mvb1 antikoerper, Tap antikoerper, Mex67h antikoerper, nuclear RNA export factor 1 antikoerper, nuclear RNA export factor 1 S homeolog antikoerper, Nuclear RNA export factor 1 antikoerper, nxf1 antikoerper, nxf1.S antikoerper, NXF1 antikoerper, LOC100113601 antikoerper, Tsp_03999 antikoerper, Nxf1 antikoerper, nxf-1 antikoerper
    Hintergrund
    This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants.

    Cellular Localization: Nucleus , nucleoplasm , Nucleus speckle , Cytoplasm
    Molekulargewicht
    70 kDa
    Gen-ID
    10482
    UniProt
    Q9UBU9
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