MAPKAP Kinase 2 Antikörper (AA 1-70)
Kurzübersicht für MAPKAP Kinase 2 Antikörper (AA 1-70) (ABIN7268665)
Target
Alle MAPKAP Kinase 2 (MAPKAPK2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-70
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Verwendungszweck
- MAPKAPK2 Rabbit pAb
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Sequenz
- MLSNSQGQSP PVPFPAPAPP PQPPTPALPH PPAQPPPPPP QQFPQFHVKS GLQIKKNAII DDYKVTSQVL
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Kreuzreaktivität
- Human, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human MAPKAPK2 (NP_116584.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))
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Andere Bezeichnung
- MAPKAPK2
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Hintergrund
- This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.,MAPKAPK2,MAPKAP-K2,MK-2,MK2,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Microtubules,Endocrine & Metabolism,Lipid Metabolism,Immunology & Inflammation,Cardiovascular,Blood,MAPKAPK2
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Molekulargewicht
- 42kDa/45kDa
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Gen-ID
- 9261
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UniProt
- P49137
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Pathways
- MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades
Target
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