MAP3K11 Antikörper (AA 140-260)
Kurzübersicht für MAP3K11 Antikörper (AA 140-260) (ABIN7268648)
Target
Alle MAP3K11 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 140-260
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Verwendungszweck
- MAP3K11 Rabbit pAb
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Sequenz
- LVAVKAARQD PDEDISVTAE SVRQEARLFA MLAHPNIIAL KAVCLEEPNL CLVMEYAAGG PLSRALAGRR VPPHVLVNWA VQIARGMHYL HCEALVPVIH RDLKSNNILL LQPIESDDME H
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Kreuzreaktivität
- Maus
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 140-260 of human MAP3K11 (NP_002410.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))
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Andere Bezeichnung
- MAP3K11
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Hintergrund
- The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.,MAP3K11,MEKK11,MLK-3,MLK3,PTK1,SPRK,Signal Transduction,Kinase,Serine/threonine kinases,Tyrosine kinases,MAPK-JNK Signaling Pathway,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,TGF-b-Smad Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,MAP3K11
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Molekulargewicht
- 65kDa/92kDa
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Gen-ID
- 4296
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UniProt
- Q16584
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Pathways
- MAPK Signalweg, Interferon-gamma Pathway
Target
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