GANP Antikörper (AA 250-550)

Produktnummer ABIN7268541

Dieses Anti-GANP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GANP in WB. Geeignet für Human.

Kurzübersicht für GANP Antikörper (AA 250-550) (ABIN7268541)

Target: GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GANP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GANP Antikörper

Bindungsspezifität: AA 250-550

Verwendungszweck: MCM3AP Rabbit pAb

Sequenz: SSFPVSSAVL GEPFQASKAG VRQGCEEAVS QVEPLPSLMK GLKRKEDQDR SPRRHGHEPA EDSDPLSRGD HPPDKRPVRL NRPRGGTLFG RTIQDVFKSN KEVGRLGNKE AKKETGFVES AESDHMAIPG GNQSVLAPSR IPGVNKEEET ESREKKEDSL RGTPARQSNR SESTDSLGGL SPSEVTAIQC KNIPDYLNDR TILENHFGKI AKVQRIFTRR SKKLAVVHFF DHASAALARK KGKSLHKDMA IFWHRKKISP NKKPFSLKEK KPGDGEVSPS TEDAPFQHSP LGKAAGRTGA S

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 250-550 of human MCM3AP (NP_003897.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GANP

Target: GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))

Andere Bezeichnung: MCM3AP

Hintergrund: The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.,MCM3AP,GANP,MAP80,SAC3,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Cell differentiation,MCM3AP

Molekulargewicht: 80kDa/218kDa

Gen-ID: 8888

UniProt: O60318

Pathways: Protein targeting to Nucleus