GANP Antikörper (AA 293-442)

Produktnummer ABIN7193448

Produktdetails anti-GANP Antikörper

Target: GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))

Bindungsspezifität: AA 293-442

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GANP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human MCM3AP (AA: 293-442) expressed in E. coli.

Klon: 5B2C4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB:1:500 - 1:2000, ELISA:1:10000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu GANP

Target: GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))

Andere Bezeichnung: MCM3AP (MCM3AP Produkte)

Synonyme: GANP antikoerper, MAP80 antikoerper, SAC3 antikoerper, mKIAA0572 antikoerper, minichromosome maintenance complex component 3 associated protein antikoerper, germinal-center associated nuclear protein antikoerper, Mcm3ap antikoerper, MCM3AP antikoerper, mcm3ap antikoerper, LOC100026233 antikoerper

Hintergrund:

Description: The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.

Aliases: GANP, SAC3, MAP80, PNRIID

Molekulargewicht: 218.4 kDa

Gen-ID: 8888

Pathways: Protein targeting to Nucleus