MAPT Antikörper (pSer416)

Produktnummer ABIN7268527

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MAPT in WB, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für MAPT Antikörper (pSer416) (ABIN7268527)

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-MAPT Antikörper

Bindungsspezifität: pSer416

Verwendungszweck: Phospho-Tau-Ser416 Rabbit pAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Phosphorylated Antibodies

Aufreinigung: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding Ser416 of human Tau.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MAPT

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Andere Bezeichnung: MAPT

Hintergrund: This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008],DDPAC;FTDP-17;MAPTL;MSTD;MTBT1;MTBT2;PPND;PPP1R103;TAU;MAPT;Tau,Apoptosis,Cell Biology & Developmental Biology,Cell Type Marker,Cell Type Marker_Axon marker,Cell Type Marker_Neural Stem Cell marker,Cell Type Marker_Neuron marker,Cytoskeleton,Cytoskeleton_Microtubules,MAPK-P38 Signaling Pathway,Neurodegenerative Diseases,Neurodegenerative Diseases_Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease,Neuroscience,Protein phosphorylation,Signal Transduction,Stem Cells,,MAPT

Molekulargewicht: 32-45kDa/78- 80kDa

Gen-ID: 4137

UniProt: P10636

Pathways: MAPK Signalweg, Microtubule Dynamics, M Phase, Regulation of Cell Size