KIFAP3 Antikörper

Produktnummer ABIN7268120

Der Kaninchen Monoklonal Anti-KIFAP3-Antikörper wurde für WB und IF validiert. Er ist geeignet, KIFAP3 in Proben von Human zu detektieren.

Kurzübersicht für KIFAP3 Antikörper (ABIN7268120)

Target: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser KIFAP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-KIFAP3 Antikörper

Verwendungszweck: KIFAP3 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human KIFAP3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KIFAP3

Target: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Andere Bezeichnung: KIFAP3

Hintergrund: The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011],FLA3, KAP-1, KAP-3, KAP3, SMAP, Smg-GDS, dJ190I16.1,Epigenetics & Nuclear Signaling,KIFAP3

Molekulargewicht: 91-100kDa

Gen-ID: 22920

UniProt: Q92845

Pathways: Hedgehog Signalweg, Sensory Perception of Sound