KIFAP3 Antikörper (Middle Region)

Produktnummer ABIN2786068

Produktdetails anti-KIFAP3 Antikörper

Target: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIFAP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: WLEMVESRQM DESEQYLYGD DRIEPYIHEG DILERPDLFY NSDGLIASEG

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against KIFAP3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KIFAP3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 792 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KIFAP3

Target: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Andere Bezeichnung: KIFAP3 (KIFAP3 Produkte)

Synonyme: CG11759 antikoerper, DmKAP antikoerper, DmKap antikoerper, Dmel\\CG11759 antikoerper, KAP antikoerper, KAP3 antikoerper, Kap antikoerper, dKAP3 antikoerper, kap3 antikoerper, FLA3 antikoerper, KAP-1 antikoerper, KAP-3 antikoerper, SMAP antikoerper, Smg-GDS antikoerper, dJ190I16.1 antikoerper, fb99h08 antikoerper, kifap3 antikoerper, wu:fb99h08 antikoerper, wz7228 antikoerper, Kinesin associated protein 3 antikoerper, kinesin-associated protein 3 antikoerper, kinesin associated protein 3 antikoerper, kinesin-associated protein 3b antikoerper, kinesin-associated protein 3 L homeolog antikoerper, Kap3 antikoerper, LOC551999 antikoerper, KIFAP3 antikoerper, Kifap3 antikoerper, kifap3b antikoerper, kifap3.L antikoerper

Hintergrund: The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras, one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein.
Alias Symbols: FLJ22818, KAP3, SMAP, Smg-GDS, dJ190I16.1, KAP-3
Protein Interaction Partner: NAA10, NCF2, UBC, PEX19, RBFOX1, KIF3A, VHL, RANBP2, MEST, DISC1, NIPSNAP3A, NUDT21, AR, RAP1GDS1, MINK1, SMC3, KIF3B, KIFAP3, MAP3K10, RPGR, SRC, APC, MAP3K11,
Protein Size: 792

Molekulargewicht: 91 kDa

Gen-ID: 22920

NCBI Accession: NM_014970, NP_055785

UniProt: Q92845

Pathways: Hedgehog Signalweg, Sensory Perception of Sound