IL-10 Antikörper

Produktnummer ABIN7267981

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch IL-10 in WB und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IL-10 Antikörper (ABIN7267981)

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser IL-10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-IL-10 Antikörper

Verwendungszweck: IL10 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human IL10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu IL-10

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Andere Bezeichnung: IL10

Hintergrund: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011],CSIF, GVHDS, IL-10, IL10A, TGIF,Apoptosis,Cancer,Cell Biology & Developmental Biology,Cell Intrinsic Innate Immunity Signaling Pathway,Cytokines,Cytokines_Interleukins,Growth factors,Immunology & Inflammation,Tumor immunology,IL10

Molekulargewicht: 18kDa

Gen-ID: 3586

UniProt: P22301

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints