This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
IRF5
(Interferon Regulatory Factor 5 (IRF5))
Andere Bezeichnung
IRF5
Hintergrund
This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Dec 2016],SLEB10,Cell Intrinsic Innate Immunity Signaling Pathway,Cytokines,Cytokines_Interferons,Epigenetics & Nuclear Signaling,Immunology & Inflammation,Transcription Factors,IRF5